BackgroundDifferent histone post-translational modifications (PTMs) are crucial in the regulation of chromatin, including methylations of H3 at Lysine 4 by the MLL complex.A relevant issue is how this is causally correlated to the binding of specific transcription factors (TFs) in regulatory regions.NF-Y is a TF that regulates 30% of mammalian prom
John H Pula,1 Katherine Kwan,2 Carlen A Yuen,3 Jorge C Kattah4 1Department of Neurology, 2Department of ophthalmology, NorthShore University HealthSystem, Evanston IL, USA; 3University of Illinois College of Medicine at Peoria, 4Department of Neurology, University of Illinois College of Medicine at Peoria, Peoria, IL, USA Abstract: Transient vision
Abstract Background The causes of an early onset of puberty are still not clearly defined and may vary from subject to subject.In girls, even if 90% of early puberty is idiopathic, magnetic resonance imaging (MRI) of the R-Alpha Lipoic Acid brain is performed to exclude secondary causes of precocious puberty, in particular pathological lesions as h
Background Better understanding of the neurobiology of posttraumatic stress disorder (PTSD) may be critical to developing novel, effective therapeutics.Here, we conducted a data-driven investigation using a well-established, graph-based topological measure of nodal strength to determine the extent of functional dysconnectivity in a cohort of active